(054) Correlation between Libido and Testosterone: Estradiol Ratio in Men with Sexual Dysfunction

Abstract Introduction Sexual desire drives men to seek sexual activity and have a positive effect on cognitive function, emotional, affective state affecting the quality of life. This dynamic process is impacted by several factors including cognitive, neurophysiological spheres. Hormonal balance, Testosterone (T) Estradiol (E), also one knownwell- known associated desire.libido. Objective Our aim was evaluate correlation between libido reduction hormonal profile (HP), Testosterone(T):Estradiol(E) ratio. Methods Retrospective analysis medical records medicine consultations in tertiary care center performed. Patients were systematically questioned if they perceived their decreased using following question (“Do you believe your or has last few months?”), all had morning HP checked (Total free testosterone, SHBG, E2, LH, FSH). categorized into groups: Low T (T 100 T:E ratio 35ng/dl) excluded. Comparison who referred those did not performed, relationship different parameters studied univariate multivariate analysis. Results Data from 273 patients available for evaluated, with amean age 61 y (± 10) y. From them, 264 (97%) reported being heterosexual 210 (77%) steady partner. this sample, 25% low levels. The percentage referring 30%. In group, 42% decrease Libido (OR 1,9; 95% IC: 1,08- 3,73; p=0,01) 52% group 3,47; 1,79-6,46; p=0,001). analysis, after adjusting age, we found libido, irrespective status. Conclusions study, our sample seeking treatment dysfunction, significantly correlated libido. Recognizing imbalance can help clinicians identify best management. Further studies are necessary confirm data, understand how affects should be addressed clinical practice. Disclosure No